Azzalure is a famous brand of botulinum toxin products. While being manufactured in Switzerland by Galderma, it is characterized by high quality, great effectiveness, and long-lasting duration.

Below, you will find the basic information, indications, contraindications, and possible side effects of Azzalure (125 Units) – a popular solution in the Azzalure product line. So, let’s discuss it right away!

Before we start: Azzalure is a brand that is primarily advertized and sold in E.U. countries. However, it might also be bought in the U.S. and Canada.

Basic Information

Azzalure (125 Units) is an injectable solution that is based on botulinum toxin (type A). It functions as a powerful muscle relaxant that is used to produce neuromuscular weakness. Therefore, the product treats patients presenting symptoms of medical and cosmetic issues related to muscle contraction.

On a side note: Botulinum toxin is a substance that is produced by the bacterium of Clostridium botulinum. While being characterized by chronic toxicity, it might become a potential cause of a dangerous disease called botulism. At the same time, however, it is employed to take care of a wide range of health and aesthetic problems.

Due to the fact that Azzalure belongs to products intended for professional use, it should be administered exclusively by healthcare professionals. According to its treatment protocol, the product should be injected intramuscularly with the help of a sterile suitable gauge needle.

On average, the result of a single Azzalure injection lasts about six months. However, its exact duration depends on the individual patient’s response to the product, health condition, age, and lifestyle. Moreover, it might be substantially prolonged by a touch-up treatment.

On a side note: Under normal circumstances, patients treated with Azzalure might undergo a touch-up treatment as soon as the result of the previous one wears off. According to numerous clinical trials, such repeated dose cycles have proven to be more efficient if compared to a single injection procedure. In most cases, the exact treatment interval depends on the individual peculiarities of a patient and should be defined by a medical professional.

A single package of the product includes two prefilled vials with 125 speywood units of Azzalure each. Due to the fact that it belongs to a single-patient treatment, a prefilled vial has to be utilized as soon as the treatment is over (even if not all the units of the product have been administered).

On a side note: Clinically relevant dose levels of Azzalure provide patients with a statistically significant difference in their health condition and appearance. Even one single-patient treatment might substantially improve a wide range of muscle-related medical and cosmetic issues.

Indications

All indications of Azzalure (125 Units) might be subdivided into medical and cosmetic ones. Check out the list of the most widely-spread ones by going through the information below.

The main medical indications of the product include:

• Neck pain;
• Excessive sweating;
• Overactive bladder;
• Teeth grinding;
• Strabismus;
• And a great number of other health problems related to muscle contraction.

On a side note: Apart from the above-mentioned medical indications, numerous Azzalure-treated patients claim that Azzalure injections significantly reduced chronic headaches. Thus, they also belong to alternative treatment methods for migraines.

While the main cosmetic indications of the product, in their turn, primarily deal with dynamic wrinkles of mild to moderate severity, such as:

• Frown lines (or, in other words, wrinkles that appear between the eyebrows);
• Nasolabial folds;
• Crows feet;
• Lateral canthal lines;
• And other wrinkles of dynamic nature.

On a side note: Azzalure has proven to be the most effective when it comes to the treatment of severe glabellar lines and severe lateral canthal lines.

Contraindications

Despite its high safety, the symptomatic treatment of Azzalure is contraindicated under one of the following circumstances:

• If a patient is below the age of eighteen;
• If a patient is currently pregnant or breastfeeding;
• If a patient is allergic or hypersensitive to botulinum toxin (or any other component of the product);
• If a patient experiences an ongoing skin infection around the proposed injection site or targeted muscle;
• If a patient lives with a serious disease (for instance, untreated epilepsy, diabetes mellitus, amyotrophic lateral sclerosis, or poor blood clotting);
• If a patient suffers from immune system disorders;
• If a patient takes incompatible medications or undergoes incompatible treatments;
• If a patient has recently undergone previous surgical interventions;
• And other limitations.

Moreover, intramuscular injections of Azzalure should by no means be performed by inexperienced healthcare practitioners. In other words, a medical worker who is going to administer the product should have a deep knowledge of a patient’s facial anatomy prior to the treatment. This way, the inappropriate injection technique and incorrect muscles injected will be avoided.

A recent update: Due to the COVID-19 pandemics, a patient tested positive for COVID-19 should postpone an Azzalure injection till the moment of their recovery.

Please note that ignorance of the above-mentioned contraindications might not only lead to treatment failure but also cause the appearance of serious complications (including muscle paralysis).

Possible Side Effects

In some cases, Azzalure leads to the appearance of certain side effects. Among the most common suspected adverse reactions to the product are:

• Localised muscle weakness around the treatment area;
• Common injection site reactions of the skin (including redness, itching, and swelling);
• Temporary paresis of facial muscles proximal to areas of the treatment;
• Light bruising around the proposed injection sites;
• Headache;
• Nausea;
• Pain or discomfort;
• And so on.

Moreover, a vast majority of patients who have undergone an injection of Azzalure claim to experience exaggerated muscle weakness for the first several days after the treatment.

Just like excessive muscle weakness, most frequent undesirable reactions that are mentioned above tend to disappear on their own within one week after the treatment and do not require any medical supervision.

On a side note: Azzalure might also have a minor or moderate influence on the work of the muscles that are located next to the treated muscle resulting in their temporary relaxation.